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Our top choices for Syracuse luxury hotels

Dimora Caiammari Luxury Hotel & Spa

Dimora Caiammari Luxury Hotel & Spa
5.0 star property
Syracuse
9.2 out of 10, Wonderful, (210)
"We experienced outstanding service from all of the staff, the breakfast buffet was lovely, lots of options and all homemade. We had a fantastic dinner in the restaurant one evening, which we booked ahead of our trip. "
United Kingdom
David
Dimora Caiammari Luxury Hotel & Spa

Charme Hotel Henry's House

Charme Hotel Henry's House
4.0 star property
Ortigia
9.6 out of 10, Exceptional, (322)
"Great location. Very friendly and helpful staff. Nice breakfast."
United States
Alan
The price is AED 955
AED 1,093 total
includes taxes & fees
28 Dec - 29 Dec
Charme Hotel Henry's House

Wellness & Spa Hotel Principe di Fitalia

Wellness & Spa Hotel Principe di Fitalia
5.0 star property
Syracuse
9.6 out of 10, Exceptional, (94)
"This was such a wonderful stay! Spotless beautiful property with friendly staff and delicious breakfast!!! Very impressed!"
United States
Jeffrey
Wellness & Spa Hotel Principe di Fitalia

Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection
5.0 star property
Ortigia
9.4 out of 10, Exceptional, (252)
"Great location and very friendly staff"
United States
James
The price is AED 810
AED 934 total
includes taxes & fees
6 Jan - 7 January 2026
Ortea Palace Hotel, Sicily, Autograph Collection

Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection
4.0 star property
Ortigia
9.4 out of 10, Exceptional, (659)
"Great hotel"
United States
Caterina
The price is AED 738
AED 854 total
includes taxes & fees
21 Dec - 22 Dec
Palazzo Artemide - VRetreats, SLH Collection

Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa
5.0 star property
Ortigia
9.0 out of 10, Wonderful, (571)
"Great stay!"
United States
Liza
The price is AED 714
AED 828 total
includes taxes & fees
7 Jan - 8 January 2026
Grand Hotel Ortigia Siracusa

Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel
4.0 star property
Ortigia
9.6 out of 10, Exceptional, (908)
"The breakfast was delicious, the staff impeccable and the room delightful. All in all an excellent stay which I would wholeheartedly recommend. "
United Kingdom
Sarah
Algila' Ortigia Charme Hotel

UNA HOTELS One Siracusa

UNA HOTELS One Siracusa
4.0 star property
Grottasanta
8.6 out of 10, Excellent, (540)
"Very nice hotel, nice sized rooms, great staff that was very helpful."
United States
Mark
The price is AED 480
AED 547 total
includes taxes & fees
21 Dec - 22 Dec
UNA HOTELS One Siracusa

Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia
9.4 out of 10, Exceptional, (257)
"Fine quality hotel with exceptional service. "
United States
Peter
The price is AED 450
AED 538 total
includes taxes & fees
5 Jan - 6 January 2026
Caportigia Boutique Hotel

Grand Hotel Villa Politi

Grand Hotel Villa Politi
4.0 star property
Grottasanta
8.6 out of 10, Excellent, (943)
"Wonderful hotel, nice area and great buffet breakfast"
United States
paula
The price is AED 403
AED 460 total
includes taxes & fees
21 Dec - 22 Dec
Grand Hotel Villa Politi
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Syracuse

Syracuseand its attractions for luxury travelers

Syracuse, Sicily, invites luxury travelers to indulge in a rich tapestry of history, culture, and exceptional experiences. Begin your exploration at the stunning Neapolis Archaeological Park, where ancient Greek ruins, including the impressive Greek Theatre, transport you back in time. Enjoy a guided tour that offers insights into the history while allowing you to marvel at the architectural grandeur. Next, visit the enchanting Ortigia Island, a UNESCO World Heritage site, where you can stroll through charming streets lined with baroque architecture, exquisite boutiques, and vibrant markets. The Piazza del Duomo, with its magnificent cathedral, is perfect for enjoying a leisurely coffee at a sidewalk café, soaking in the local ambiance. For art enthusiasts, the Museo Archeologico Regionale Paolo Orsi showcases ancient artifacts, including exquisite sculptures and pottery, all set in a beautifully designed space. After a day of exploration, unwind at luxury hotels in Ortigia, such as the historic Grand Hotel Ortigia, where you can savor stunning sea views and exceptional service. The area boasts access to exclusive dining experiences, including Michelin-starred restaurants that offer a taste of Sicilian cuisine paired with fine wines. With its combination of rich history, breathtaking architecture, and high-end hospitality, Syracuse promises a captivating getaway that caters to travelers.

Find the best luxury hotels and resorts in Syracuse

For travelers seeking a luxurious escape in Syracuse, Sicily, these top hotels offer exquisite amenities and unparalleled comfort, ensuring a memorable stay in this stunning destination.

Algila' Ortigia Charme Hotel

  • Why it's great for a luxury retreat: Ideal for luxury travelers, Algila' Ortigia Charme Hotel enchants guests with its breathtaking sea views and impeccable service. With an impressive review rating of 9.6, this hotel features a 24-hour room service and a well-stocked minibar, ensuring guests have everything they need at their fingertips. The concierge is always on hand to assist with local insights and exclusive arrangements, making every stay tailored and unique.
  • Other amenities: In addition to its luxurious offerings, guests can enjoy valet parking for added convenience, air conditioning for comfort, and access to a nearby beach for relaxation. The hotel also provides complimentary breakfast daily, ensuring a delightful start to each day. Other features include a private hot tub, daily housekeeping, and a charming balcony for soaking in the stunning surroundings.
  • Neighborhood: Ortigia
  • Nearby attractions: Ionian Sea - 0.15 miles, Lungomare di Ortigia - 0.16 miles, Cathedral of Syracuse - 0.6 miles

Palazzo Artemide - VRetreats

  • Why it's great for a luxury retreat: Palazzo Artemide - VRetreats is a luxurious haven in Ortigia, an elegant Beaux Arts design and a stellar review rating of 9.4. This hotel is perfect for guests who appreciate high-end amenities, such as valet parking and concierge services, ensuring a seamless experience from arrival to departure. Premium bedding guarantees a restful night’s sleep, making it an ideal retreat for travelers.
  • Other amenities: Beyond the luxury, guests can enjoy easy access to the sandy beach nearby, with various boat tours available for exploration. The hotel also offers daily housekeeping and complimentary cribs for families, ensuring comfort for all. With its historical district location, travelers can immerse themselves in the rich culture of Syracuse with ease.
  • Neighborhood: Ortigia
  • Nearby attractions: Lungomare di Ortigia - 0.86 miles, Cathedral of Syracuse - 0.32 miles, Castello Maniace - 0.66 miles

Grand Hotel Ortigia Siracusa

  • Why it's great for a luxury retreat: For luxury seekers, Grand Hotel Ortigia Siracusa offers an exquisite stay with a review rating of 9.0. This hotel is characterized by its stunning sea views and premium bedding, ensuring a restful and picturesque experience. Guests can indulge in in-room massages and champagne service, perfect for a romantic getaway or a special occasion. The concierge is available to assist with arranging local activities, enhancing the overall stay.
  • Other amenities: In addition to its high-end amenities, the hotel features a rooftop terrace with breathtaking views, a full-service spa, and a fitness center for those looking to maintain their wellness regimen while traveling. The nearby various waterfront locations and historical sites allows guests to explore the beauty and culture of Syracuse effortlessly.
  • Neighborhood: Ortigia
  • Nearby attractions: Ionian Sea - 0.09 miles, Temple of Apollo - 0.2 miles, Piazza del Duomo - 0.25 miles

Grand Hotel Villa Politi

  • Why it's great for a luxury retreat: Grand Hotel Villa Politi stands out as a luxurious option for travelers in Grottasanta, featuring upscale amenities and a review rating of 8.6. Guests will appreciate the designer toiletries and air conditioning, providing a touch of elegance and comfort throughout their stay. The concierge service is readily available to assist with any requests, ensuring that every need is met promptly and with care.
  • Other amenities: Additional luxurious features include a beautiful terrace for enjoying the views, a complimentary buffet breakfast, and daily housekeeping services. Guests can also explore the nearby beach and enjoy the serene garden area for relaxation. The hotel combines modern comforts with classic charm, making it a distinguished choice in Syracuse.
  • Neighborhood: Grottasanta
  • Nearby attractions: Pista Ciclabile Siracusa - 0.38 miles, Museo Archeologico Regionale Paolo Orsi - 0.67 miles, Porto Piccolo - 0.79 miles

Grande Albergo Alfeo

  • Why it's great for a luxury retreat: Grande Albergo Alfeo is an elegant choice for travelers desiring luxury in Santa Lucia, an impressive review rating of 8.6. Guests will enjoy the Art Deco design and the personalized service from the concierge. The hotel offers spacious suites that provide a comfortable and opulent environment, perfect for unwinding after a day of exploration.
  • Other amenities: Additional amenities include a charming garden with views, complimentary breakfast options, and nearby parking for convenience. The hotel is strategically located near historical sites and the beach, allowing guests to immerse themselves in the local culture while enjoying luxurious comforts. With daily housekeeping and quality toiletries, every detail contributes to an exceptional stay.
  • Neighborhood: Santa Lucia
  • Nearby attractions: Ionian Sea - 0.59 miles, Temple of Apollo - 0.54 miles, Porto Piccolo - 0.37 miles

Top Syracuse Hotel Reviews

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Frequently asked questions

Are you searching for a great accommodation for your luxury holiday in Syracuse?
Travel to Fontanarossa Airport (CTA) Airport or Vincenzo Magliocco Airport (CIY) Airport, and then treat yourself to a stay at one of 5 Syracuse luxury hotels. While you're visiting, you might want to think about enjoying the ruins and sightseeing, which Syracuse is known for.
What's the best high-end place to stay in Syracuse?
Grand Hotel Des Ètrangers - The Leading Hotels of the World is a luxury hotel with a full-service spa and a seasonal outdoor pool, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Grand Hotel Ortigia Siracusa and Dimora Caiammari Luxury Hotel & Spa are other upscale choices for your vacation.
How many luxury hotels will I be able to find in Syracuse?
Lie in the lap of luxury during your getaway to Syracuse in one of Expedia's 5 luxury hotels.
When can I expect good weather in Syracuse?
Planning for the weather is a good way to make your trip to Syracuse relaxing and enjoyable, especially when you're splurging. The hottest months are usually August and July with an average temp of 78°F, while the coldest months are February and January with an average of 56°F. Average annual precipitation for Syracuse is 26 inches.
What's there to see and do in Syracuse?
Experience all that Syracuse has to offer when you visit Temple of Apollo, Lungomare di Ortigia, and Piazza del Duomo. If you have a little extra time during your trip, you might want to check out Cathedral of Syracuse and Porto Piccolo.
How can I get around Syracuse?
It's easier to get around town in style when you know your options. To explore the surrounding area, ride one of the trains from Syracuse Station or Targia Station.