Are there any 5-star all-inclusive resorts in Syracuse?

Our filter tool is the easiest way to find exactly what you want. Select "5-star" and "All inclusive" to show the most luxurious properties in Syracuse where your accommodations, meals, activities and entertainment are included in the price. At these retreats, your vacation is pure extravagance from the moment you check in.

What are the top 5-star spa hotels in Syracuse?

Syracuse has a range of 5-star spa accommodations that offer therapies designed to revitalize both the mind and body. Spend your next vacation at Minareto , Ortea Palace, Sicily, Autograph Collection or Grand Hotel Ortigia Siracusa and prioritize your health and well-being.

Are there any 5-star vacation rentals in Syracuse?

You won't find any 5-star vacation rentals in Syracuse on our site, but there are a few other highly rated properties worth checking out. Browse our vacation rentals in Syracuse to book the perfect place for your stay.

Are there any 5-star hotels in downtown Syracuse?

Book a room at Grand Hotel Ortigia Siracusa . This 5-star hotel is an excellent option if you want to experience Syracuse's exciting downtown scene.

The Best 5 Star Hotels in Syracuse from AED 485

Syracuse, panoramic phot of the Roman Amphitheatre at Syracuse (Siracusa), UNESCO World Heritage Site, Sicily, Italy, Europe

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Our top choices for Syracuse 5-star hotels

Grand Hotel Ortigia Siracusa

Ortigia

Yuqi

AED 1,362 total

includes taxes & fees

17 May - 18 May

Ortea Palace Hotel, Sicily, Autograph Collection

Ortigia

Max

AED 2,121 total

includes taxes & fees

12 May - 13 May

Caportigia Boutique Hotel

Santa Lucia

Brian

AED 890 total

includes taxes & fees

12 May - 13 May

Sauna, hot tub, Turkish bath, body treatments, body scrubs, facials

Dimora Caiammari Luxury Hotel & Spa

Syracuse

Jing

AED 1,376 total

includes taxes & fees

11 May - 12 May

Seasonal outdoor pool, pool umbrellas, sun loungers

Grand Hotel Des Ètrangers - The Leading Hotels of the World

Ortigia

Dena

AED 2,339 total

includes taxes & fees

14 May - 15 May

Minareto

Syracuse

Stanislau

AED 1,418 total

includes taxes & fees

3 Jun - 4 Jun

Wellness & Spa Hotel Principe di Fitalia

Syracuse

Jeffrey

AED 1,484 total

includes taxes & fees

18 May - 19 May

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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Syracuse.

Algila' Ortigia Charme Hotel

Via Vittorio Veneto 93 Syracuse SR

AED 1,314

AED 1,489 total

17 May - 18 May

includes taxes & fees

9.6/10 Exceptional! (951 reviews)

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Pool Spa Hot tub Breakfast included Waterpark

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Syracuse

Ancient Greek ruins in the Archaeological Park include the impressive Teatro Greco where summer performances still take place. Wander through Ortygia's narrow streets to discover the Duomo, built around a former Greek temple with columns still visible from inside.

See all hotels in Syracuse

Top Syracuse Hotel Reviews

Grand Hotel Des Ètrangers - The Leading Hotels of the World

10/10 Excellent

"Delightful hotel with wonderful attentive staff, beautiful food and comfortable Ed’s. Can highly recommend 🙌"

Ortea Palace Hotel, Sicily, Autograph Collection

6/10 Okay

"The in-room WiFi wasn’t working and they said it wouldn’t be working. That the in-room was a third party and they had no control!! Out coffee table was about to fall apart. Maintenance did come to try and save it but they couldn’t. So we had to live with it for the duration of our stay. The bar was never staffed and we had to go search for someone to assist. This is not a 5 star or 4 star hotel. It is in desperate need of help"