Are there any 5-star all-inclusive resorts in Syracuse?

Our filter tool is the easiest way to find exactly what you want. Select "5-star" and "All inclusive" to show the most luxurious properties in Syracuse where your accommodations, meals, activities and entertainment are included in the price. At these retreats, your vacation is pure extravagance from the moment you check in.

What are the top 5-star spa hotels in Syracuse?

Syracuse has a range of 5-star spa accommodations that offer therapies designed to revitalize both the mind and body. Spend your next vacation at Minareto , Ortea Palace, Sicily, Autograph Collection or Grand Hotel Ortigia Siracusa and prioritize your health and well-being.

Are there any 5-star vacation rentals in Syracuse?

You won't find any 5-star vacation rentals in Syracuse on our site, but there are a few other highly rated properties worth checking out. Browse our vacation rentals in Syracuse to book the perfect place for your stay.

Are there any 5-star hotels in downtown Syracuse?

Book a room at Grand Hotel Ortigia Siracusa . This 5-star hotel is an excellent option if you want to experience Syracuse's exciting downtown scene.

The Best 5 Star Hotels in Syracuse from AED 450

Panorama View of the Fortress Castello Maniace on Ortygia Island, Syracuse, Italy - UNESCO World Heritage

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Our top choices for Syracuse 5-star hotels

Grand Hotel Ortigia Siracusa

Ortigia

Yuqi

AED 1,515 total

includes taxes & fees

29 Jun - 30 Jun

Ortea Palace Hotel, Sicily, Autograph Collection

Ortigia

Joe

AED 1,747 total

includes taxes & fees

5 Jul - 6 Jul

Seasonal outdoor pool, pool umbrellas, sun loungers

Grand Hotel Des Ètrangers - The Leading Hotels of the World

Ortigia

Leanne

AED 2,258 total

includes taxes & fees

28 Jun - 29 Jun

Sauna, hot tub, Turkish bath, body treatments, body scrubs, facials

Dimora Caiammari Luxury Hotel & Spa

Syracuse

Jing

AED 1,158 total

includes taxes & fees

29 Jun - 30 Jun

Caportigia Boutique Hotel

Santa Lucia

Valerie

AED 824 total

includes taxes & fees

6 Jul - 7 Jul

Minareto

Syracuse

Stanislau

AED 1,539 total

includes taxes & fees

25 Jun - 26 Jun

Wellness & Spa Hotel Principe di Fitalia

Syracuse

Jeffrey

AED 1,508 total

includes taxes & fees

2 Jul - 3 Jul

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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Syracuse.

Algila' Ortigia Charme Hotel

Via Vittorio Veneto 93 Syracuse SR

AED 718

AED 832 total

20 Jul - 21 Jul

includes taxes & fees

9.6/10 Exceptional! (972 reviews)

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Pool Spa Hot tub Breakfast included Waterpark

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Syracuse

Ancient Greek ruins in the Archaeological Park include the impressive Teatro Greco where summer performances still take place. Wander through Ortygia's narrow streets to discover the Duomo, built around a former Greek temple with columns still visible from inside.

See all hotels in Syracuse

Syracuse, panoramic phot of the Roman Amphitheatre at Syracuse (Siracusa), UNESCO World Heritage Site, Sicily, Italy, Europe

Top Syracuse Hotel Reviews

Ortea Palace Hotel, Sicily, Autograph Collection

10/10 Excellent

"Clean, good service, nice location"

Minareto

10/10 Excellent

"Beyond the hotel’s stunning and breathtaking views, the customer service was truly exceptional—both attentive and highly responsive. I would easily rate them 120%! I absolutely loved the jacuzzi and its location, which made the experience even more special. Both of the rocky and sandy beaches were unique and incredibly relaxing. Their boat service also made commuting by sea to Ortigia a truly phenomenal experience. If interested, they offer scooter, e-bike, and kayak…"

Frequently asked questions

What are the best 5-star hotels in Syracuse?

Prepare for 5-star opulence at Grand Hotel Ortigia Siracusa, Ortea Palace, Sicily, Autograph Collection or Grand Hotel Des Ètrangers. These are some of the best stays in Syracuse based on Expedia customer reviews. Book one and get a taste of the finer life!

How much does it cost to stay in a 5-star hotel in Syracuse?

How much you pay for a 5-star hotel in Syracuse depends on factors like when you plan to go and the length of your vacation. Our insider tip for bagging the best deal? Use our pricing filters to compare all of the available hotels for your preferred dates.

Search for the lowest price per night from AED 450

What makes a hotel 5 stars in Syracuse?

From high-end restaurants and fitness centers to swimming pools and superior bedding, the 5-star experience in Syracuse is all about luxury and relaxation. But it calls for more than just upscale amenities to get a 5-star rating. Hotels also have to deliver outstanding guest services like massage treatments, laundry and dry cleaning and 24-hour room service.

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