Find All Southeast Missouri Hotels
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Find All Southeast Missouri Hotels
We have found 642 Southeast Missouri Hotels
- Drury Plaza Hotel Cape Girardeau Conference Center
- Silo Farm Haus- located in the heart of wine country!
- The Riverview
- Drury Inn & Suites Sikeston, MO
- Drury Inn & Suites Cape Girardeau
- La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
- Drury Inn & Suites Jackson MO
- Baymont Inn and Suites by Wyndham Farmington, MO
- Motel 6 Poplar Bluff, MO
- The Farmstead Hotel
- Pear Tree Inn Cape Girardeau West
- Drury Inn & Suites Poplar Bluff
- La Quinta Inn & Suites by Wyndham Festus - St. Louis South
- Quality Inn Cape Girardeau North
- Fairfield Inn & Suites by Marriott Cape Girardeau
- Courtyard by Marriott Cape Girardeau Downtown
- Candlewood Suites Cape Girardeau by IHG
- Drury Inn & Suites Hayti Caruthersville
- Comfort Inn Festus - St Louis South
- Century Casino & Hotel Caruthersville
- Best Western Plus Sikeston I-55
- Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
- Crown Pointe Lodge, BW Signature Collection
- Fairfield Inn & Suites by Marriott Poplar Bluff
- Holiday Inn Express & Suites Perryville by IHG
- Tru By Hilton Cape Girardeau
- Microtel Inn & Suites by Wyndham Sainte Genevieve
- Comfort Suites Jackson-Cape Girardeau
- Echo Bluff State Park
- Baymont by Wyndham Festus
- Hampton Inn Cape Girardeau I 55 East
- Hampton Inn Farmington
- Super 8 by Wyndham Farmington
- Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
- Super 8 by Wyndham Perryville
- Holiday Inn Express & Suites Sikeston Southwest by IHG
- Holiday Inn Poplar Bluff by IHG
- Super 8 by Wyndham Sikeston/Miner Area
- Town House Inn Cape Giradreau
- Country Yard Inn and Suite
- Honeysuckle Inn - Mountain View
- Super 8 by Wyndham Pevely
- Fairfield Inn & Suites by Marriott Sikeston
- New Orleans Inn Portageville
- Hampton Inn By Hilton Dexter
- Travelodge by Wyndham Dexter
- Econo Lodge Kennett
- Quality Inn Farmington
- Holiday Inn Express & Suites Farmington by IHG
- Super 8 by Wyndham Bonne Terre
- Days Inn by Wyndham Perryville
- Motel 6 Bonne Terre, MO
- Town House Inn
- Super 8 by Wyndham Poplar Bluff Missouri
- Days Inn & Suites By Wyndham Festus
- Quality Inn Hayti North
- Dexter Inn
- Shepherd Mountain Inn
- Super 8 by Wyndham Charleston/Sikeston East MO
- Econo Lodge Dexter
- TownePlace Suites by Marriott Sikeston
- Travel Inn
- Super 8 By Wyndham Marston
- Comfort Inn & Suites Sikeston I-55
- The Riverstone Hotel Charleston-Sikeston
- Current River Inn
- YMCA Trout Lodge
- Fort Davidson Hotel
- Quality Inn Perryville I-55
- EC Reed's Mercantile and Hotel
- Triangle Inn Motel
- Arcadia Academy
- Azaria Lodge - Sleeps up to 38 People - Keep Everyone Together as you Celebrate!
- Rockwood Inn
- The Weber Farm - Enjoy a beautiful 100 acre farm!
- Spring Lake Ranch has a Private, Rustic Lodge perfect for family/group retreats!
- The Cottage Room has 2 queen beds and private bathroom
- Peaceful 3-bedroom lodge that sleeps up to 10 on a private lake.
- Wilderness Lodge
- OYO Hickory House Inn
- Black River Motel and Restaurant
- Bullwinkles Rustic Lodge
- Super 8 by Wyndham Kennett
- Relax with the whole family at Puckett’s View- Potosi, MO - Home Away From Home.
- Cute and comfy bedroom with 1 queen bed/private bath
- 1-bedroom farm stay just 6 minutes to Ozark National Scenic Riverways
- The Woods and Willow Room. 1 queen bed ..cot can be added and private bathroom
- OYO Malden Airport Inn