A large white building with a dome and a statue in front, surrounded by fountains and trees.

Find 5 Star Hotels in St. Louis, MO from AED 508

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Check availability on St. Louis 5 Star Hotels

Tonight
3 Oct - 4 Oct
Tomorrow
4 Oct - 5 Oct
Next weekend
9 Oct - 11 Oct
In two weeks
16 Oct - 18 Oct

Our top choices for St. Louis 5-star hotels

A modern hotel lobby with a glass facade, seating area, and a staircase.
A room with large windows overlooking a bridge and water, featuring wooden chairs and a small table.
A couple relaxing by a window overlooking a bridge and water.
A bar area with a bartender, a bar counter with various bottles, and a view of the Gateway Arch.

1. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
United States
Nicole
AED 1,377
AED 1,611 total
includes taxes & fees
4 Oct - 5 Oct
Four Seasons Hotel St Louis
An indoor dining area with a long table, chairs, hanging plants, and a view of a brick building through large windows.
A modern living room with a sofa, chairs, a coffee table, and a chandelier.
A lobby with a fireplace, two armchairs, a round table, and a bench.
An outdoor seating area with modern furniture, a bar, and large windows offering views of a cityscape.

2. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
United States
Kennedy
AED 2,127
AED 2,483 total
includes taxes & fees
1 Nov - 2 Nov
The Ritz-Carlton, St. Louis
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in St. Louis.
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

9801 Natural Bridge Road St. Louis MO
AED 434
AED 508 total
18 Oct - 19 Oct
includes taxes & fees
Renaissance St. Louis Airport Hotel
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

315 Chestnut St St. Louis MO
AED 526
AED 620 total
30 Oct - 31 Oct
includes taxes & fees
Hyatt Regency St. Louis at The Arch
21C Museum Hotel St Louis

21C Museum Hotel St Louis

1528 Locust street St. Louis MO
AED 528
AED 635 total
25 Oct - 26 Oct
includes taxes & fees
21C Museum Hotel St Louis
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

St. Louis and related destinations

The Gateway Arch towers 630 feet above the Mississippi, with a tram that takes you to spectacular views at the top. Explore Forest Park's free museums, catch a Cardinals game at Busch Stadium, and don't miss Ted Drewes' frozen custard that locals swear by.

See all hotels in St. Louis
A large white building with a dome and a statue in front, surrounded by fountains and trees.

Top St. Louis Hotel Reviews

Frequently asked questions

What are the best 5-star hotels in St. Louis?
Boasting first-rate amenities and guest services, our customers rate Four Seasons Hotel St Louis as among the best 5-star hotels in St. Louis. You'll be immersed in a world of luxury from the moment you step foot into the lobby.
How much does it cost to stay in a 5-star hotel in St. Louis?
There are a range of pricing options for 5-star hotels in St. Louis on Expedia. How much you'll pay will depend on your vacation dates, trip length and other factors. Compare all of the available accommodations for your chosen dates and make use of our pricing and other filters to find the perfect luxury stay.
  • Search for the lowest price per night from AED 508
What makes a hotel 5 stars in St. Louis?
In St. Louis, a hotel needs to offer a certain number of upscale features to be rated 5 stars. These may include on-site gyms, spas and saunas, gourmet restaurants, luxury bathroom products, premium bedding and more. What also sets 5-star hotels apart is their guest-centric service. You can expect things like concierge services, in-room massages and nightly turn-down services. Some may also offer additional touches like welcome gifts.

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