The Best 4 Star Hotels in Upstate South Carolina, SC from AED 410 | Expedia

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Check availability on Upstate South Carolina 4 Star Hotels

Tonight

12 Jul - 13 Jul

Tomorrow

13 Jul - 14 Jul

Next weekend

17 Jul - 19 Jul

In two weeks

24 Jul - 26 Jul

Our top choices for Upstate South Carolina 4-star hotels

Exterior

Grand Bohemian Lodge Greenville, Autograph Collection

Greenville Downtown

United States

Brian

AED 1,453 total

includes taxes & fees

5 Aug - 6 Aug

Lobby

The Shepherd Hotel Downtown Clemson

Clemson

United States

Amy

AED 571 total

includes taxes & fees

13 Jul - 14 Jul

Restaurant

Hotel Hartness

Greenville

United States

Vlatka

AED 808 total

includes taxes & fees

19 Jul - 20 Jul

Exterior

The Westin Poinsett Greenville

Greenville Downtown

United States

Kristina

AED 660 total

includes taxes & fees

26 Jul - 27 Jul

Bar (on property)

Greenville Marriott

Greenville

United States

Towana

AED 509 total

includes taxes & fees

19 Jul - 20 Jul

Deluxe Two Bedroom (Self Check-in with Virtual Front Desk) | Living area | 55-inch flat-screen TV with digital channels, TV, streaming services

Mint House Greenville Downtown by Kasa

Greenville Downtown

United States

NEOLA

AED 410 total

includes taxes & fees

5 Aug - 6 Aug

Lobby lounge

The Abernathy of Clemson

Clemson

United States

Samuel

AED 614 total

includes taxes & fees

2 Aug - 3 Aug

Trailside Wedge Cottage | Terrace/patio

The Station by Compo Hotels

Travelers Rest

United States

Martin

AED 1,219 total

includes taxes & fees

13 Jul - 14 Jul

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Learn more about Upstate South Carolina

Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Discovery Island Water Park to Frankie's Fun Park.

See all hotels in Upstate South Carolina

An aerial view of a park with a winding path, trees in autumn colors, and a bridge.

Top Upstate South Carolina Hotel Reviews

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

10/10 Excellent

"Amazing stay and staff and nice rooms"

Hotel Hartness

Hotel Hartness

8/10 Good

"I have loved this hotel since it opened, and I have given it rave reviews in the past. I stay at least once a year, but this trip was definitely a surprise. If you are a repeat guest and you haven’t been around since December, then you’ll be sad to find as I was that the vibe has changed from what I think made it so special into much more of a Corporate hotel. There was always a breakfast that was free and everybody would gather around eat together, Chat, meet each other like a community. It truly represented the vibe and feel of this property. Sadly that is gone now to almost a Starbucks like counter with prices behind the board and a shopping area.. While I appreciate having an area where I can buy popcorn and drinks if I would like that, it completely changes what made this hotel so special. You can get past that with the amazing restaurant fantastic spa gorgeous ROOMS and refreshing Pool. Sadly, the pool service, which used to have amazing food, with a person there and a bar downstairs seems now at least during the week,, (also Friday) not available any longer. There was just a small little menu and everybody walking all the way up to the building to bring their own drinks down. Not the end of the world but definitely another change that isn’t the spirit of this hotel and both of these decisions made this particular trip, lacking. The property is beautiful, beds are comfortable. Restaurant is fantastic. The staff iA+ it was just better before. Solid B+ to A~"

Frequently asked questions

What are the best 4-star hotels in Upstate South Carolina?

Greenville Marriott is rated highly by many Expedia guests. Located in Greer, Upstate South Carolina, this 4-star hotel features lots of amenities to help make your stay comfortable and convenient.

How much does it cost to stay in a 4-star hotel in Upstate South Carolina?

Expedia can help you quickly locate the perfect 4-star hotel for your getaway in Upstate South Carolina. Use our handy filter tool to tailor your search by things like amenities, budget and property star rating and get access to fabulous deals in a few clicks.

Search for the lowest price from AED 410

What's the difference between 5-star and 4-star hotels in Upstate South Carolina?

Offering a friendly guest experience and upmarket décor, 4-star hotels are a wonderful option for your Upstate South Carolina trip. These kinds of accommodations generally come with loads of handy amenities that make it simple to kick back and relax — think large beds, bathrobes, restaurants and pools. Or live the high life at a 5-star hotel designed to pamper with exclusive perks and amenities. Full-service health clubs, premium toiletries and fine dining are typically featured at these deluxe retreats.

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Upstate South Carolina Hotels by Star Rating

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