Find hotels in Mesopotamia from AED 228

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Our top choices for Mesopotamia hotels

To Spiti tis Sofias

To Spiti tis Sofias
Kastoria
10.0 out of 10, Exceptional, (1)
"Tout simplement le meilleur de notre voyage en Grèce. Simple mais tellement mieux qu'ailleurs. Accueil parfait, chambre confortable et petit déjeuner de roi. Je reviendrais à 100% si je passe dans le coin. "
France
Anonymous traveler
The price is AED 247
AED 283 total
includes taxes & fees
8 Jan - 9 January 2026
To Spiti tis Sofias

Guesthouse Monopati

Guesthouse Monopati
Amyntaio
10.0 out of 10, Exceptional, (3)
Guesthouse Monopati

Limneon Resort & Spa

Limneon Resort & Spa
4.0 star property
Kastoria
9.2 out of 10, Wonderful, (197)
"Wonderful stay. "
Canada
Konstantinos
The price is AED 365
AED 427 total
includes taxes & fees
8 Jan - 9 January 2026
Limneon Resort & Spa

Kyknos De Luxe Hotel

Kyknos De Luxe Hotel
Kastoria
10.0 out of 10, Exceptional, (43)
"Very nice clean, very polite staff and great breakfast!"
United States
Vasilios
The price is AED 335
AED 387 total
includes taxes & fees
23 Jan - 24 January 2026
Kyknos De Luxe Hotel

Guest House Ilektra

Guest House Ilektra
Voio
9.6 out of 10, Exceptional, (9)
"Wonderful views, easy to find, spacious rooms, and great hospitality."
United Kingdom
Maria
The price is AED 223
AED 256 total
includes taxes & fees
30 Dec - 31 Dec
Guest House Ilektra

Esperos Palace Luxury & Spa Hotel

Esperos Palace Luxury & Spa Hotel
4.0 star property
Kastoria
9.0 out of 10, Wonderful, (84)
"The hotel is beautiful, large room with balcony. Grate bathroom, comfortable, the dinner is good ,however the breakfast was amazing. "
United States
Michal
Esperos Palace Luxury & Spa Hotel

Chloe Hotel

Chloe Hotel
3.0 star property
Kastoria
10.0 out of 10, Exceptional, (87)
"We enjoyed the stay, friendly staff and nice breakfast "
Australia
Fani
The price is AED 373
AED 430 total
includes taxes & fees
23 Jan - 24 January 2026
Chloe Hotel

Calma Hotel & Spa

Calma Hotel & Spa
4.0 star property
Kastoria
9.6 out of 10, Exceptional, (35)
"Pleasant stay. Good amenities. Great staff. "
New Zealand
Robert
Calma Hotel & Spa

Guesthouse Vissinokipos

Guesthouse Vissinokipos
Kastoria
9.4 out of 10, Exceptional, (10)
"Wonderfull view and very friendly people.the place is avery dpecial artistic decorated.wonderfull weather.nice varieties for breakfast.price was ver good.i recommend it!"
United States
Carmen
Guesthouse Vissinokipos

Anesis Hotel

Anesis Hotel
2.0 star property
Kastoria
9.0 out of 10, Wonderful, (9)
"Fantastic hotel in the heart of Kastoria. The owners are lovely people, very helpful and made me feel right at home. Will definitely stay there again!"
Canada
Adam
The price is AED 199
AED 228 total
includes taxes & fees
23 Jan - 24 January 2026
Anesis Hotel

Andromeda Boutique hotel

Andromeda Boutique hotel
4.0 star property
Kastoria
8.8 out of 10, Excellent, (3)
Andromeda Boutique hotel

The Sunset Haven Kastoria Modern Lake Elegance

The Sunset Haven Kastoria Modern Lake Elegance
Kastoria
The Sunset Haven Kastoria Modern Lake Elegance
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mesopotamia Hotel Reviews

More cheap stays in Mesopotamia

Hotels in Mesopotamia with star-rating

Find out more about Mesopotamia

Top reasons to visit Mesopotamia

  • Scenic Beauty: Mesopotamia is known for its picturesque landscapes, featuring stunning lakes and natural surroundings that are perfect for outdoor exploration.
  • Rich Cultural Experience: The region offers intriguing history museums and notable landmarks, allowing visitors to delve into its vibrant heritage.
  • Outdoor Adventures: Enjoy a variety of activities that cater to both thrill-seekers and those looking for relaxation amidst nature.
  • Charming Village Atmosphere: Experience the warm hospitality of locals in this delightful village setting.
  • Diverse Accommodation Options: Mesopotamia provides a range of hotels, from budget-friendly to luxurious, ensuring a comfortable stay for all travelers.

Find great hotels near Mesopotamia

In Mesopotamia, you'll discover a variety of hotels tailored to meet the needs of both business travelers and those seeking adventure or a relaxing spa-themed getaway. Whether you're looking for the best hotels or affordable accommodations, this area offers a range of options with competitive room rates. Experience the charm and hospitality of Mesopotamia as you find the perfect place to stay during your vacation in this picturesque region of Western Macedonia, Greece.

  • Esperos Palace Luxury & Spa Hotel: Nestled a mere 8.0km from Mesopotamia, the Esperos Palace Luxury & Spa Hotel offers a serene retreat for those seeking relaxation and rejuvenation. With a strong emphasis on wellness, this 4-star property boasts an extensive spa featuring treatment rooms, couples' massage options, and accessible pool facilities. Ideal for business travelers and vacationers alike, the hotel provides a sophisticated atmosphere complemented by professional services, ensuring a tranquil and indulgent experience.
  • Hotel Anastassiou: Just 8.0km from Mesopotamia, Hotel Anastassiou is the perfect choice for adventure seekers and ski enthusiasts. This hotel combines comfort with excitement, offering easy access to ski lifts and a variety of outdoor activities, including hiking, fishing, and waterskiing. With its focus on adventure sports, guests can enjoy an exhilarating stay filled with recreation opportunities both onsite and nearby, making it a fantastic option for those looking to blend business travel with thrilling experiences.
  • Kyknos De Luxe Hotel: Located 8.0km from Mesopotamia, Kyknos De Luxe Hotel is a 3.5-star accommodation that caters to luxury and business travelers. This stylish hotel features elegant rooms and modern amenities that provide a comfortable and sophisticated atmosphere. Whether you're in town for a corporate event or a leisurely getaway, Kyknos De Luxe ensures a high standard of service and comfort, making it a fitting choice for discerning guests in search of a luxurious stay.

Where to stay in Mesopotamia

Mesopotamia, a charming village in Western Macedonia, Greece, offers a delightful blend of scenic beauty and outdoor adventures, perfect for romantic getaways. Nearby cities and neighborhoods provide a vibrant atmosphere, catering to families and travelers seeking budget-friendly, trendy, or luxurious experiences. Explore the stunning landscapes and enjoy the warm hospitality of the local people, making your visit to Mesopotamia an unforgettable journey through this picturesque region.

  • Kastoria: Nestled in the picturesque landscape of Western Macedonia, Kastoria is a city that offers a unique blend of outdoor adventure and rich history. Known for its stunning mountainous scenery, visitors are drawn to its natural beauty and opportunities for activities like skiing and spa retreats. The city is home to historic places and monasteries that enrich the travel experience. The best time to visit is during the peak months of September and November to December, when the weather is ideal for exploration.
  • Árgos Orestikón: Located a mere 9.7km from Mesopotamia, Árgos Orestikón is a charming city that invites adventurers and outdoor enthusiasts alike. With its scenic valleys, the area provides ample opportunities for hiking and nature walks. The city’s visitor numbers peak in September and during the winter months of December to January, making it an appealing choice for those looking to embrace the natural landscape without the crowds. Experience the local culture and warm hospitality as you explore this hidden gem.
  • Dispilio: Just 11.3km from Mesopotamia, the village of Dispilio is a delightful destination for those seeking a mix of beach and adventure. Known for its proximity to beautiful lakes and museums, visitors can enjoy a variety of activities, including skiing at nearby resorts. The village sees a moderate spike in visitors from July to September, ideal for enjoying the summer sun. Whether you're looking to ski or relax by the water, Dispilio offers an inviting escape into nature's embrace.

Things to do in Mesopotamia

Mesopotamia offers a picturesque setting perfect for outdoor and romantic getaways. Visitors can enjoy thrilling experiences at the local amusement park and explore available trips that highlight the region's stunning scenery and rich culture. Whether you're seeking adventure or relaxation, Mesopotamia promises an unforgettable vacation filled with unique activities and breathtaking views.

Shopping

In Mesopotamia, enjoy local shops offering unique gifts and souvenirs. If you're up for a drive, visit the Kastoria Shopping Center, about 19.3km away, where you can find a diverse selection of boutiques and artisanal products that showcase the region's rich culture.

Recreation

Explore the serene waters of Lake Vegoritida for kayaking and paddleboarding, surrounded by stunning landscapes. Unwind at local wellness centers offering traditional Greek massages and rejuvenating treatments, enhancing your relaxation experience in the tranquil atmosphere of Mesopotamia's nature.

Adventure

Explore the stunning landscapes of Mesopotamia with a hike along the scenic trails, offering breathtaking views of the countryside. Experience local culture by visiting traditional villages and engaging in outdoor activities like kayaking in serene waters or cycling through picturesque routes.

Nightlife

Experience the vibrant nightlife in Mesopotamia by visiting La Bottega for exquisite cocktails. For a lively atmosphere, check out Café Bar Nefeli, where you can enjoy local wines and live music, creating the perfect setting for a memorable night out.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Mesopotamia

To save money on your trip to Mesopotamia, consider visiting during the cheaper months of March and October to November. Book your hotel about a month in advance for the best rates, and look for last-minute deals on Expedia. Tuesdays are typically the least expensive days to stay, while Thursdays are the priciest. Use Expedia’s search tool to filter hotels by price and combine bookings for flights and activities to unlock additional savings. Additionally, explore free activities in the area to maximize your budget while enjoying your vacation.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Mesopotamia are March and October to November, where the prices are slightly lower. This is in comparison to April and July to August, where prices are slightly higher.
  • The best time to book a hotel: The cheapest time to book a hotel in Mesopotamia is usually 1 month out from when you are planning to stay, though if you're late to the party, have a look at Expedia's last minute deals - the green banner below the hotel's price indicates a discounted rate.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Mesopotamia is Tuesday. The most expensive day to stay in Mesopotamia is Thursday.
  • Find cheap hotels on Expedia: Utilize Expedia’s search tool to customize your preferences, such as your budget, desired location, and ideal hotel type. To find the best prices and deals, simply arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your Mesopotamia hotel reservation with your flights and activities through an Expedia package deal.

Find the best attractions near Mesopotamia

Mesopotamia, located in Kastoria, Western Macedonia, Greece, is perfect for a scenic and romantic getaway. Visitors can enjoy a variety of attractions, including beautiful lakes, intriguing history museums, and notable landmarks. The region offers a rich cultural experience, along with opportunities for outdoor adventures, making it an ideal destination for travelers seeking a blend of relaxation and exploration.

  • Kastoria Lake: Nestled just 8.0km from Mesopotamia, Kastoria Lake offers a romantic escape with its stunning scenery. Enjoy leisurely walks along the tranquil shores, relax on the beach, and soak in the breathtaking views that change with the seasons.
  • Folklore Museum of Kastoria: Located 8.0km away, this museum is a treasure trove of local culture. Experience the rich history of Kastoria through its diverse exhibits, showcasing traditional costumes, crafts, and artifacts that reflect the region's vibrant heritage.
  • Taxiarhia of the Metropolis: A mere 8.0km from Mesopotamia, this landmark combines trendy allure with a luxurious ambiance. Explore its architectural beauty while enjoying budget-friendly options, making it accessible for all visitors.

Best time to go to Mesopotamia

The best time to visit Mesopotamia is dependent on what kind of holiday you are seeking. August is its hottest month on average. At this time, visitor numbers are moderately high and weather is sunny with no rain. January is its coolest month on average. At this time, visitor numbers are moderately low and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January32.5°F (0.3°C)Light RainMostly SunnyModerately LowAverage
February36.1°F (2.3°C)Light RainMostly SunnyModerately LowAverage
March41.7°F (5.4°C)Light RainMostly SunnyAverageSlightly Low
April50.2°F (10.1°C)Light RainMostly SunnyAverageSlightly High
May57.9°F (14.4°C)Light RainMostly SunnyAverageAverage
June66.0°F (18.9°C)No RainMostly SunnyAverageAverage
July72.3°F (22.4°C)No RainSunnyModerately HighSlightly High
August72.5°F (22.5°C)No RainSunnyModerately HighSlightly High
September64.2°F (17.9°C)No RainMostly SunnyModerately HighAverage
October54.1°F (12.3°C)Light RainMostly SunnyAverageSlightly Low
November45.1°F (7.3°C)Light RainMostly SunnyModerately LowSlightly Low
December36.3°F (2.4°C)Light RainMostly SunnyAverageAverage

The nearest major airports for your trip to Mesopotamia

For travelers heading to Mesopotamia, the two major airports to consider are Kozani (KZI-Filippos) and Kastoria (KSO-Aristoteles). Kozani Airport is located 61.2km from Mesopotamia, with nearby hotel options like the 3-star Elimeia 3, 14.5km away, and Anesis Hotel, just 3.2km from the airport. Kastoria Airport is closer at 11.3km from Mesopotamia, featuring luxury accommodations such as the 5-star Limneon Resort & Spa, 4.8km away, and the Orologopoulos Mansion, 8.0km distant. Many hotels near Kastoria offer convenient transportation services, including 24-hour shuttles and airport transfers, ensuring a smooth travel experience.

Frequently asked questions

Where is the best place for a stay in Mesopotamia?
To Spiti tis Sofias is one of the top choices for your stay based on our traveler data. This guesthouse offers free parking and free WiFi. Two other choices for your visit to the area are Limneon Resort & Spa and Hotel Anastassiou. See all available top hotels, or vacation rentals in Mesopotamia.
What are some of the best vacation home rentals that Mesopotamia has to offer?
The Sunset Haven Kastoria Modern Lake Elegance: This vacation home rental outside of Mesopotamia offers a barbecue grill and free WiFi to help you feel comfortable in your new surroundings. See all vacation rentals in Mesopotamia.
If I need to cancel my hotel reservation in Mesopotamia, will I receive a refund?
Yes! You'll find that most room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Mesopotamia.
Where can I learn more about changing or cancelling my trip to Mesopotamia?
For more details about picking new dates or cancelling your trip to Mesopotamia, click here.
What is the best accommodation for staying close to Macedonia Airport (SKG)?
Hyatt Regency Thessaloniki is a popular 5-star hotel featuring 2 outdoor pools and a full-service spa. It's located a short 1.1 mi (1.8 km) from Macedonia Airport. Other options near the airport are Athina Airport Hotel and Hotel Nikopolis.
What is staying in Mesopotamia like?
Travelers to Mesopotamia will find plenty to explore and enjoy. There are 46 hotels and other accommodations in the surrounding area. Find out more about Mesopotamia.
What are the top places to visit in Mesopotamia?
Places to visit in the wider area include Kastoria Aquarium, Kastoria Lake, and Dragon's Lair. You'll also find Folklore Museum of Kastoria and Neolithic Lakeside Settlement in the area. Check out what more to see and do in Expedia's Mesopotamia guide.
What's the seasonal weather like in Mesopotamia?
The hottest months are usually August and July with an average temp of 69°F, while the coldest months are January and February with an average of 37°F. Average annual precipitation for Mesopotamia is 28 inches.

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