Find Resorts & Hotels with Spas in Greenville, SC

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Our top choices for Greenville hotels with a spa

Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection
4.0 star property
Greenville Downtown
9.6 out of 10, Exceptional, (444 reviews)
  • cleanliness
    Escape to a Tudor retreat with a full-service spa and rooftop garden overlooking the scenic river in Greenville.
The price is AED 951
AED 1,075 total
includes taxes & fees
23 Feb - 24 Feb
Grand Bohemian Lodge Greenville, Autograph Collection

Hotel Hartness

Hotel Hartness
4.0 star property
Greenville
9.8 out of 10, Exceptional, (644 reviews)
  • cleanliness
    Indulge in rejuvenating treatments at this upscale hotel with six couples spa rooms and scenic hiking trails for a peaceful escape.
The price is AED 589
AED 772 total
includes taxes & fees
8 Feb - 9 Feb
Hotel Hartness

Hotel Domestique

Hotel Domestique
4.0 star property
Travelers Rest
9.8 out of 10, Exceptional, (31 reviews)
  • cleanliness
    Retreat to this mountain hotel with therapeutic massage treatments, sauna, and seasonal outdoor pool for deep relaxation.
The price is AED 1,172
AED 1,289 total
includes taxes & fees
8 Feb - 9 Feb
Hotel Domestique

The Orchard Inn

The Orchard Inn
3.0 star property
Saluda
9.4 out of 10, Exceptional, (139 reviews)
  • cleanliness
    Enjoy a couples massage or solo Swedish retreat in this peaceful bed & breakfast with gardens and a 24-hour gym.
The Orchard Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Choose what matters most at spa hotels in Greenville

Find out more about Greenville

Top Greenville attractions for a relaxing vacation

Travelers seeking a rejuvenating getaway in Greenville, South Carolina, will find themselves enchanted by the city's blend of natural beauty and urban charm. Start your adventure at Falls Park on the Reedy, where you can stroll along scenic pathways and marvel at the stunning waterfalls. For culture enthusiasts, the Greenville County Museum of Art offers a serene atmosphere with impressive American art collections, perfect for a leisurely afternoon. If you're looking for a taste of local flavors, the bustling Swamp Rabbit Trail leads you to various farm-to-table restaurants that highlight the region’s culinary scene. Families can enjoy the interactive exhibits at the Children's Museum of the Upstate, ensuring a fun day out for all ages. As you explore, consider staying in the vibrant West End district, known for its boutique hotels with spa services, which provide the perfect balance of relaxation and convenience. Here, the attentive guest service and luxurious amenities will cater to your every need, allowing for a truly pampered experience as you unwind after a day of exploration.

Find the best hotels & resorts with spas in Greenville

For travelers seeking relaxation and rejuvenation in Greenville, South Carolina, these top hotels offer exceptional spa amenities and a tranquil atmosphere.

Hotel Hartness

  • Why it's great for tailored spa getaway: Hotel Hartness is the ultimate retreat for spa enthusiasts, featuring a breathtaking review rating of 9.8. Guests can indulge in a range of spa services, including body treatments, massages, and facial treatments, all delivered in serene treatment rooms designed for ultimate relaxation. The full-service spa ensures a luxurious experience, including couples treatment rooms for a romantic escape.
  • Other amenities: Beyond the spa, guests can enjoy a beautiful terrace, a shared pool with secured access, and 24-hour fitness facilities. Additional features include complimentary premium bedding, designer toiletries, and hydromassage showerheads in the rooms. Guests can also take advantage of the concierge service, highchair availability for younger guests, and electric car charging stations to enhance their stay.
  • Nearby attractions: Pelham Mills Site - 2.55 miles, LeMans Karting - 2.65 miles

Grand Bohemian Lodge Greenville, Autograph Collection

  • Why it's great for tailored spa getaway: The Grand Bohemian Lodge Greenville offers a luxurious spa experience with a stellar review rating of 9.6. The on-site full-service spa provides a variety of treatments daily, ensuring that guests can unwind and recharge during their stay. The elegant design of the lodge complements the soothing spa environment, making it a perfect getaway for rejuvenation.
  • Other amenities: Guests can enjoy a rooftop garden, 24-hour fitness facilities, and valet parking for added convenience. The hotel also features balconies or patios, air conditioning, and premium bedding for a comfortable stay. Daily housekeeping ensures that guests’ needs are met, while a concierge service is available to assist with any arrangements during their visit.
  • Neighborhood: Greenville Downtown
  • Nearby attractions: The Peace Center - 0.4 miles, Falls Park on the Reedy - 0.0 miles, Fluor Field at the West End - 0.9 miles

Top Greenville Hotel Reviews

Frequently asked questions

Looking to vacation at a spa hotel in Greenville?
Treat yourself to some pampering and book a hotel with a spa. Travelers highly recommend Greenville for its array of shops and gourmet restaurants—your day tour starts here. Enjoy the live music and waterfalls during your vacation. Hotels with spas are a great way to take a break from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Greenville?
Grand Bohemian Lodge Greenville, Autograph Collection is a top spa hotel featuring a 24-hour fitness center, a bar, and a restaurant. Another popular spa hotel in Greenville is Hotel Hartness.
How many spa hotels will I find in Greenville?
Among Expedia's 684 accommodation options in Greenville, there are 2 spa hotels.
What's there to see and do in Greenville?
Take in the sights and attractions that Greenville offers with a visit to The Peace Center, The Children's Museum of the Upstate, and Bon Secours Wellness Arena. If you have some spare time during your trip, you might want to check out Greenville Zoo and Fluor Field at the West End.
What is a Greenville spa hotel?
Spa hotels in Greenville have full on-site spas and offer services like couples massages and a choice of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are a must if you want to give yourself an extra treat while on vacation.