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Find Resorts & Hotels with Spas in Central San Diego, CA

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Check availability on Central San Diego Resorts & Hotels with Spas

Our top choices for Central San Diego hotels with a spa

Front of property - evening/night

Handlery Hotel

Handlery Hotel
3.5 star property
Mission Valley
8.4 out of 10, Very Good, (2,737 reviews)
  • cleanliness
    Surrender to spa treatments and poolside luxury at this hotel with massage rooms and a beautiful heated outdoor pool and hot tub.
The price is AED 493
AED 566 total
includes taxes & fees
19 Aug - 20 Aug
Handlery Hotel
Couples treatment rooms, body treatments, hot stone massages

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (3,100 reviews)
  • cleanliness
    Indulge in a serene escape at this upscale hotel with a full-service spa, outdoor pool with free cabanas, and couples massage treatments.
The price is AED 724
AED 832 total
includes taxes & fees
2 Aug - 3 Aug
Legacy Resort Hotel & Spa
Dinner served

Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark
4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (2,277 reviews)
  • cleanliness
    Rooftop spa retreat delivers poolside massages and soothing therapies in the heart of downtown San Diego.
The price is AED 555
AED 810 total
includes taxes & fees
27 Jul - 28 Jul
Omni San Diego Hotel at the Ballpark
Couples treatment rooms, body treatments, aromatherapy

Estancia La Jolla Hotel & Spa

Estancia La Jolla Hotel & Spa
4.0 star property
La Jolla Farms
9.0 out of 10, Wonderful, (405 reviews)
  • cleanliness
    Discover a tranquil garden retreat with luxurious spa treatments and a serene outdoor pool for the ultimate pampering getaway in La Jolla.
The price is AED 1,208
AED 1,604 total
includes taxes & fees
16 Aug - 17 Aug
Estancia La Jolla Hotel & Spa
Reception

Humphreys Half Moon Inn

Humphreys Half Moon Inn
3.5 star property
Point Loma
9.2 out of 10, Wonderful, (3,053 reviews)
  • cleanliness
    Escape to this bayfront sanctuary with deep-tissue massages, a serene hot tub, and an outdoor pool for complete relaxation.
The price is AED 786
AED 977 total
includes taxes & fees
18 Aug - 19 Aug
Humphreys Half Moon Inn
Hot stone massages, prenatal massages, sports massages, body scrubs

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay
8.6 out of 10, Excellent, (1,522 reviews)
  • cleanliness
    Unwind at this bay-view resort offering garden massages, poolside lounging, and a rejuvenating full-service spa retreat.
The price is AED 1,025
AED 1,372 total
includes taxes & fees
16 Aug - 17 Aug
San Diego Mission Bay Resort
Exterior

Best Western Plus Island Palms Hotel & Marina

Best Western Plus Island Palms Hotel & Marina
3.0 star property
Point Loma
9.0 out of 10, Wonderful, (1,599 reviews)
  • cleanliness
    Blissful bay views and relaxing massages set the scene for a restorative escape at this waterfront sanctuary with bubbling hot tubs.
The price is AED 684
AED 787 total
includes taxes & fees
6 Aug - 7 Aug
Best Western Plus Island Palms Hotel & Marina
Premium bedding, in-room safe, desk, laptop workspace

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
National City
9.2 out of 10, Wonderful, (3,938 reviews)
  • cleanliness
    Indulge in bay-side spa services and hot tub relaxation at this tranquil hotel where pampering treatments meet scenic marina views.
The price is AED 625
AED 689 total
includes taxes & fees
17 Aug - 18 Aug
Best Western Plus Marina Gateway Hotel
5 outdoor pools, a heated pool, pool umbrellas, sun loungers

Paradise Point Resort & Spa

Paradise Point Resort & Spa
4.0 star property
Mission Bay
8.8 out of 10, Excellent, (2,739 reviews)
  • cleanliness
    Immerse in waterfront tranquility with hot stone massages and aromatherapy at this resort spa retreat.
The price is AED 974
AED 1,314 total
includes taxes & fees
16 Aug - 17 Aug
Paradise Point Resort & Spa
Couples treatment rooms, sauna, hydrotherapy, aromatherapy, body wraps

Catamaran Resort and Spa

Catamaran Resort and Spa
4.0 star property
Mission Beach
8.6 out of 10, Excellent, (1,318 reviews)
  • cleanliness
    Luxurious beachside retreat offers 10 spa treatment rooms, waterfront yoga, and a serene bay location for ultimate wellness.
The price is AED 984
AED 1,327 total
includes taxes & fees
19 Aug - 20 Aug
Catamaran Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Central San Diego

Pool
Breakfast included

Top Central San Diego Hotel Reviews

The Alcala Hotel Mission Valley/Seaworld

The Alcala Hotel Mission Valley/Seaworld

10/10 Excellent
"This was one of the best stays I’ve ever had. So clean & the staff was amazing!"
Corwin 3-night trip
Posted 1 hour ago
The Alcala Hotel Mission Valley/Seaworld

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