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Find All Southern Illinois Hotels
We have found 1161 Southern Illinois Hotels
- Holiday Inn Express & Suites Vandalia by IHG
- Comfort Inn & Suites Carbondale University Area
- Suite Dreams Motel Mattoon I 57
- Extended Stay America Select Suites - St. Louis - O' Fallon, IL
- First Western Inn
- Super 8 by Wyndham Mt. Vernon IL
- Holiday Inn Effingham by IHG
- Clarion Pointe Mattoon near University
- Super 8 by Wyndham Belleville St. Louis Area
- Comfort Inn & Suites Greenville I-70
- Super 8 by Wyndham Pontoon Beach IL/St. Louis MO Area
- Cobblestone Inn & Suites - Altamont
- Days Inn by Wyndham Troy IL
- Ramada by Wyndham Vandalia
- Quality Inn & Suites Salem near I-57
- Quality Inn & Suites Mattoon South
- Fairfield Inn and Suites by Marriott Marion
- Super 8 by Wyndham Collinsville St. Louis
- Hampton Inn Collinsville
- Best Western U. S. Inn
- Days Inn by Wyndham Pontoon Beach
- Days Inn & Suites by Wyndham Casey
- Comfort Suites Effingham Central
- Pinckeyville Inn and Suites
- Motel 6 Mount Vernon, IL
- Home2 Suites By Hilton Effingham
- Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
- Days Inn by Wyndham Charleston
- Country Garden & Suites
- Indoor Heated Pool pontoon boat fish 3 full baths sleeps 17 in beds 2026 SALE!!!
- Super 8 by Wyndham Greenville
- Motel 6 Metropolis, IL
- Days Inn & Suites by Wyndham Caseyville
- Fairfield Inn by Marriott St. Louis Collinsville, IL
- SureStay Hotel by Best Western Greenville
- Super 8 by Wyndham Okawville
- Hotel 7 Inn Anna
- Laketree Inn And Suites Marion
- Americas Best Value Inn West Frankfort
- TownePlace Suites by Marriott St. Louis Edwardsville, IL
- The Shelby Inn
- Eighteen-Ninety Sleepover
- Fairfield Inn & Suites Marriott Effingham
- Super 8 by Wyndham Waterloo
- Super 8 by Wyndham Du Quoin
- Super 8 by Wyndham Marshall
- Bel Air Motel
- Super 8 by Wyndham Harrisburg
- Rodeway Inn Effingham North
- Budget Host Inn Greenup
- Budget Motel Granite City/St Louis Area
- Innkeeper Motel
- Loyalty Inn Maryville
- Red Bud Country Inn
- Best Western Flora Inn
- Charleston House Bed & Breakfast Inn
- Wine Country Farmhouse On the Wine 🍷 Trail! Private Lake kayaks Fire Pit 🔥
- Powhatan Motel
- ECONOMY INN
- Super 8 by Wyndham Salem
- First Western Inn Caseyville
- Americas Best Value Inn Vandalia
- Budget Inn by Hotel O Greensville I 70
- Quality Inn Carbondale University area
- Motel 6 Troy, IL
- Makanda Inn
- Relax Inn
- centralia motel
- Briarwood Inn of Sparta
- Baymont by Wyndham Metropolis
- Super 8 by Wyndham Olney
- Super 8 by Wyndham Mt. Carmel IL
- Traveler's Inn Motel
- Royal INN
- Lighthouse Lodge
- The Conner House B&B
- Quality Inn Grayville
- Spillway Motel
- Eagles Crossing is a Newly Renovated 3-Bed Farmhouse with a Large Deck & Hot Tub
- Royal Inn
- Capital O Sparta Motel Near Carbondale
- Americas Best Value Inn Mount Vernon
- Americas Best Value Inn Marion, IL
- Stunning 8-bedroom barndo on a 24-acre farm with pond, located on wine trail
- Cozy Farmhouse with 4 Bedrooms and 3 Baths
- Quality Inn Cairo I-57
- Trailway Motel