Find 4 Star Hotels in Florida Keys

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Florida Keys 4 Star Hotels

This weekend
Next weekend

Our top choices for Florida Keys 4-star hotels

Reefhouse Resort & Marina

Reefhouse Resort & Marina
4.5 star property
Key Largo
9.4 out of 10, Exceptional, (1,472 reviews)
"We loved this place! The view, the access to everything, the food, would definitely stay here again!"
United States
Thomas
The price is AED 804
AED 1,052 total
includes taxes & fees
28 Jun - 29 Jun
Reefhouse Resort & Marina

Hawks Cay Resort

Hawks Cay Resort
4.0 star property
Marathon
8.2 out of 10, Very Good, (1,006 reviews)
"Perfect for our family, staff was amazing and the property is beautiful"
United States
Kathryne
The price is AED 751
AED 1,127 total
includes taxes & fees
6 Jul - 7 Jul
Hawks Cay Resort

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
4.0 star property
Key Largo
8.6 out of 10, Excellent, (1,106 reviews)
"Great stay over Spring Break. Beautiful place!"
United States
Angela
The price is AED 937
AED 1,257 total
includes taxes & fees
14 Jul - 15 Jul
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Amara Cay Resort

Amara Cay Resort
4.0 star property
Matecumbe
8.8 out of 10, Excellent, (1,291 reviews)
"Good place to stay, very friendly staff and great breakfast!"
United Kingdom
Christos
The price is AED 598
AED 941 total
includes taxes & fees
7 Jul - 8 Jul
Amara Cay Resort

Islander Resort

Islander Resort
4.0 star property
Matecumbe
9.4 out of 10, Exceptional, (1,059 reviews)
"Beautiful rooms and resort."
United States
Neha
The price is AED 940
AED 1,306 total
includes taxes & fees
6 Jul - 7 Jul
Islander Resort

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
4.0 star property
Marathon
8.6 out of 10, Excellent, (1,169 reviews)
"Amazing location and super pet friendly!"
United States
Thalia
The price is AED 512
AED 714 total
includes taxes & fees
15 Jul - 16 Jul
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
4.5 star property
Rock Harbor
9.0 out of 10, Wonderful, (1,004 reviews)
"Our favorite hotel in the FL Keys"
United States
Jose
The price is AED 1,113
AED 1,455 total
includes taxes & fees
8 Jul - 9 Jul
Playa Largo Resort & Spa, Autograph Collection

Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort
4.0 star property
Marathon
8.8 out of 10, Excellent, (1,004 reviews)
"Fantastic place, great atmosphere, peaceful, fantastic staff and the view was great!"
United States
Michael J
The price is AED 967
AED 1,326 total
includes taxes & fees
19 Jul - 20 Jul
Tranquility Bay Beachfront Hotel and Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
4.0 star property
Islamorada
9.0 out of 10, Wonderful, (214 reviews)
"Room was beautiful, just as pictured on the website. It is a lovely place."
United States
CATHY
The price is AED 1,027
AED 1,424 total
includes taxes & fees
13 Jul - 14 Jul
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

La Siesta Resort & Villas

La Siesta Resort & Villas
4.0 star property
Matecumbe
8.6 out of 10, Excellent, (1,008 reviews)
"Our families really enjoyed our stay there new favorite"
United States
Marc
The price is AED 674
AED 1,027 total
includes taxes & fees
7 Jul - 8 Jul
La Siesta Resort & Villas

Villas At Hawks Cay Resort

Villas At Hawks Cay Resort
4.0 star property
Marathon
8.2 out of 10, Very Good, (212 reviews)
"We had a great stay."
United States
Elise
The price is AED 2,564
AED 3,112 total
includes taxes & fees
24 Jun - 25 Jun
Villas At Hawks Cay Resort

Grassy Flats Resort & Beach Club

Grassy Flats Resort & Beach Club
4.0 star property
Marathon
9.4 out of 10, Exceptional, (460 reviews)
"Great location, beautiful room with sea view balcony. Would stay again"
United Kingdom
Katherine
The price is AED 656
AED 914 total
includes taxes & fees
23 Jun - 24 Jun
Grassy Flats Resort & Beach Club

The Islands of Islamorada

The Islands of Islamorada
4.0 star property
Matecumbe
9.6 out of 10, Exceptional, (76 reviews)
"What a wonderful venue for our last 2 nights in the Keys. This place is a hidden gem. The entire staff, especially Edith, the bartender, were fantastic."
United States
Michael
The price is AED 2,347
AED 2,843 total
includes taxes & fees
6 Jul - 7 Jul
The Islands of Islamorada

The Reef at Marathon, Florida Keys

The Reef at Marathon, Florida Keys
4.0 star property
Marathon
9.2 out of 10, Wonderful, (32 reviews)
"Great location! "
United States
Ricardo
The Reef at Marathon, Florida Keys

Marlin Bay Resort & Marina

Marlin Bay Resort & Marina
4.5 star property
Marathon
10.0 out of 10, Exceptional, (3 reviews)
"Wonderful vacation!"
United States
Chardell
Marlin Bay Resort & Marina

Waterfront Luxury Villa

Waterfront Luxury Villa
4.0 star property
Marathon Shores
Waterfront Luxury Villa

Florida Keys Getaway w/ Stunning Ocean Views

Florida Keys Getaway w/ Stunning Ocean Views
4.0 star property
Long Key
Florida Keys Getaway w/ Stunning Ocean Views
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Florida Keys

Snorkel crystal-clear waters teeming with colorful fish, then feast on fresh-caught lobster at a laid-back waterfront shack. Drive the scenic Overseas Highway, stopping at Key West's Ernest Hemingway Home and Dry Tortugas National Park for island adventures.

Top Florida Keys Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Florida Keys?
If your Florida Keys adventure is in Key Largo, stay at Playa Largo Resort & Spa, Autograph Collection. With lots of amenities such as a firepit and a pillowtop mattress, it earns top marks from many Expedia travelers. Another sought-after option here is Bakers Cay Resort Key Largo, Curio Collection by Hilton. It's also rated 4 stars and features a steam room and a swimming pool.
How much does it cost to stay in a 4-star hotel in Florida Keys?
To find a 4-star hotel in Florida Keys that fits your budget, take advantage of Expedia's handy search filters. Take a look at the availability during your vacation dates and use our pricing filter to set your maximum rate. You can also sort your results by the most affordable retreat first.

  • Search for the lowest price

What's the difference between 5-star and 4-star hotels in Florida Keys?
Offering a welcoming traveler experience and upmarket décor, 4-star hotels are an excellent option for your Florida Keys getaway. These types of accommodations generally feature loads of useful amenities that make it easy to unpack and relax — think pillowtop mattresses, pools and restaurants. Or live the high life at a 5-star hotel designed to spoil you with high-end perks and amenities. Concierge assistance, premium toiletries and fine dining are typically included at these deluxe properties.

Explore a world of travel with Expedia